Lumpy skin disease (LSD) (nodular dermatitis of cattle) is a contagious, highly dangerous infectious disease, which is characterised by persistent fever, lymphatic system damage, hypostases of subcutaneous tissue and internals, nodules on the skin, mucosal membranes and internals, eyes damage. It is included in the list of cross-border animal diseases (TADs). LSD also is a subject to obligatory notification in OIE, by reason of an extensive economic damage to livestock production and due to serious trade restrictions leading to an international trade failure in most heavily affected regions. Lumpy skin disease is an endemic disease for the majority of the countries in Africa (for a long time it was widespread only to the south of the Sahara). Since 2012 it has been extending to the countries of the Middle East, the Balkans, Eastern Europe, Russia and Kazakhstan promptly. This work provides data analysis on distribution of outbreaks of nodular dermatitis, in particular in the northern direction (Eastern Europe and Russia), moreover about the ways of virus transmission and risk factors depending on conditions of every region.