The increase in aneuploidy of embryos Is associated with pathological morphology of the sperm

Chromosomes of embryos of couples with reduced number of morphologically normal sperm cells (less than 4%) and couples with a normal level of morphologically normal sperm cells (over 4%) has revealed significant differences. In the group with a low level of normal spermatozoa, the frequency of embryos with normal chromosomes is significantly reduced and incidence of sex chromosome trisomies and autosomal monosomies and trisomies is increased; a tendency to decrease has been found for the frequency of male embryos. The obtained data may be useful to establish additional criteria for preimplantation genetic screening in the case of male infertility. © 2017, Pleiades Publishing, Inc.

Авторы
Kiseleva Y.Y. 1, 2 , Azova M.M. 2 , Kodyleva T.A.1 , Kirillova A.O.1, 3 , Ekimov A.N.1 , Rakitko A.S.3 , Mishieva N.G.1 , Abubakirov A.N.1
Редакторы
-
Издательство
-
Номер выпуска
12
Язык
Английский
Страницы
1378-1381
Статус
Опубликовано
Подразделение
-
Номер
-
Том
53
Год
2017
Организации
  • 1 Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Moscow, 117997, Russian Federation
  • 2 Department of Biology and Genetics, Peoples’ Friendship University of Russia (RUDN University), Moscow, 117198, Russian Federation
  • 3 Department of Embryology, Moscow State University, Moscow, 119991, Russian Federation
Ключевые слова
aneuploidy; genetic screening; IСSI; sperm morphology
Дата создания
19.10.2018
Дата изменения
19.10.2018
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/5147/