Estradiol-17β receptors in cytosolic fraction of chondrosarcoma

Estradiol-17β receptors were detected in the cytosolic fraction of the majority of bone chondrosarcomas by protamine sulfate sedimentation of the hormone-receptor complex. The absolute number of receptors in tumors was higher in men than in women, but chondrosarcomas with estradiol-17β receptors more often occurred in women. The highest level of receptors was revealed in highly differentiated chondrosarcomas. No relationships between tumor location, size, type of the process, and the number of receptors was detected. We can state with assurance that the absence of estradiol-17β receptors in chondrosarcomas in women is a favorable prognostic sign with regard to metastases or local tumor relapses.

Авторы
Редакторы
-
Издательство
New York Consultants BureauSpringer / Автономная некоммерческая организация Издательство Российской академии медицинских наук
Номер выпуска
2
Язык
Английский
Страницы
174-175
Статус
Опубликовано
Подразделение
-
Номер
-
Том
129
Год
2000
Организации
  • 1 N. N. Blokhin Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russian Federation
  • 2 Medical Faculty, Russian University of Peoples' Friendship, Moscow, Russian Federation
Ключевые слова
Chondrosarcoma; Estradiol-17β receptors; Prediction
Дата создания
19.10.2018
Дата изменения
19.10.2018
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/493/