Clinical control of packed RBC transfusion in acute surgical pathology such as gastric dilation and volvulus in dogs
The main goal of the present work was the analysis of peripheral blood in case of surgical pathology in dogs with gastric dilation and volvulus as well as correction of post-operative state by RBC transfusion. Scientific supplies of domestic and foreign authors that influenced the use of blood transfusion and control of various types of correction in life-threatening conditions served as methodological basis of the scientific study. The studies used methods of clinical examination characterizing the pathogenetic aspects of the problem being studied. During the period of post-op observation of the animals anemia was detected on Day 1-7, thrombocytopenia on Day 1-3, as well as severe immunosuppression caused by the development of anesthesia and splenectomy, which was confirmed by lymphopenia and thrombocytopenia on Day 1-3. The study has shown that the use of packed red blood cells in the early post-op period reduces the severity of anemia, and the severity of the inflammatory process. Administration of donor red blood cells reduces immunosuppressive effect of splenectomy and effects of general anesthesia, triggers the production of platelets, reticulocytes, thereby stimulating cell proliferation to the reparative processes. The use of packed red blood cells in case of severe abdominal pathology in dogs in the post-op period is a promising direction for the development of hemotransfusion in the veterinary surgery.