Unusual transformations of 1-vinyl-4,5,6,7-tetrahydro-5-methyl-4,6- ethanopyrrolo[3,2-c]pyridine to cyclohepteno[b]pyrroles under acetylation conditions

Heating 1-vinyl-4,5,6,7-tetrahydro-5-methyl-4,6-ethanopyrrolo[3,2-c]pyridme (1) in the presence of acetic or trifluoroacetic anhydride resulted in bicyclic saturated fragment cleavage, affording cyclohepteno[b]pyrroles 2a,b in low yields. In the case of trifluoroacetic anhydride, the major product of the reaction, -trifluoroacetylsubstituted tetrahydropyrrolo[3,2-c]pyridine 3 was isolated in 34% yield.

Редакторы
-
Журнал
Издательство
-
Номер выпуска
2 SPEC.ISS.
Язык
Английский
Страницы
147-150
Статус
Опубликовано
Подразделение
-
DOI
-
Номер
-
Том
2000
Год
2000
Организации
  • 1 Organic Chemistry Department, Russ. Peoples Friendship University, 3, Ordzhonikidze St., 117419 Moscow, Russian Federation
Ключевые слова
1 vinyl 4,5,6,7 tetrahydro 5 methyl 4,6 ethanopyrrolo[3,2 c]pyridine; acetic acid; acid anhydride; pyridine derivative; pyrrole derivative; trifluoroacetic acid; unclassified drug; acetylation; article; chemical analysis; chemical structure; heating; reaction analysis; structure analysis; substitution reaction
Дата создания
19.10.2018
Дата изменения
19.10.2018
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/407/