Aspects of Salmonellosis pathogenesis using chicken models

Salmonellosis (also called "a disease of civilization") is widespread across the globe, including the Russian Federation. Hence, measures to lower the morbidity of human beings, animals, and to limit propagation of infectious causative agents are needed. We studied colonization resistance and Salmonella typhimurium No5715 dissemination into chickens' tissues and organs. The duration of the experiment was 30 days. We identified microorganisms to study colonization resistance of bowels and salmonella dissemination into chickens' tissues and organs. We used the microscope "H604T Trinocular Unico" for morphological studies. We noticed acute and subacute course of salmonellosis, extensive vessel hemorrhages, cyanosis, hyperemia, numerous dotted and spotted hemorrhages in chickens' tissues and organs. Pathological signs developed were accidental transformation of thymus, bursa of Fabricius' atrophy, hyperplasia of the spleen, catarrhal-hemorrhagic pericarditis, air sacculusis, enteritis, perihepatitis, stagnant hemorrhagic infarct of kidneys. Common symptoms of infection were observed, such as exudation and infiltration, increase of plasma clumps, macrophage reactions, perivascular edema, and disseminated thrombosis. The study confirms that salmonellosis is a dangerous disease that can affect many organs and requires etiologic and pathogenetic treatment.

Авторы
Редакторы
-
Журнал
Издательство
UNIV UDAYANA
Номер выпуска
1
Язык
Английский
Страницы
206-210
Статус
Опубликовано
Подразделение
-
Ссылка
-
Номер
-
Том
8
Год
2019
Организации
  • 1 Moscow State Univ Food Prod, Volokolamskoe Highway 11, Moscow 125080, Russia
  • 2 Peoples Friendship Univ Russia, RUDN Univ, 6 Miklukho Maklaya St, Moscow 117198, Russia
  • 3 Fed Ctr Anim Hlth, Mkr Yuryevets St Inst Town 33, Vladimir 600901, Russia
  • 4 Moscow State Acad Vet Med & Biotechnol MVA, Moscow 109472, Russia
  • 5 Saratov State Agrarian Univ, 1 Theater Sq, Saratov 410012, Russia
  • 6 Russian State Social Univ, 4 Wilhelm Pik St, Moscow 129226, Russia
  • 7 All Russian Res Inst Physiol Biochem & Nutr Anim, Borovsk 249013, Russia
Ключевые слова
salmonellosis; diagnostics; etiological structure; epizootic situation; chickens
Дата создания
19.07.2019
Дата изменения
19.07.2019
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/39300/