Clinico-pharmacological characteristics of opioid drug-drug interactions in cancer patients with chronic pain syndrome

The aim of the review was to analyze published studies on the impact of opioid drug-drug interactions on the choice of analgesic therapy regimens. Material and methods. A systematic literature search was conducted using PubMed, Scopus, Web of Science, and E-library databases. results. the review showed a clinical significance of pharmacokinetic interactions of opioids with other drugs in cancer pain treatment. the problems of individual choice of analgesics from different groups under conditions of co-morbidity and concomitant medication were discussed to ensure the effectiveness/safety of the treatment strategy affecting the quality of life of cancer patients. Conclusion. A comprehensive assessment of factors in patients receiving opioid analgesics is a predictor of effective and safe analgesic therapy. © 2019 Tomsk National Research Medical Center of the Russian Academy of Sciences. All rights reserved.

Авторы
Bobrova O.P.1, 2 , Shnayder N.A.3 , Zyryanov S.K. 4 , Dykhno Y.A.1, 2 , Petrova M.M.1 , Nasyrova R.F.3
Редакторы
-
Издательство
Tomsk National Research Medical Center of the Russian Academy of Sciences
Номер выпуска
6
Язык
Русский
Страницы
114-122
Статус
Опубликовано
Подразделение
-
Номер
-
Том
17
Год
2018
Организации
  • 1 Krasnoyarsk State Medical University of the Health Ministry of the Russian Federation, 1, P. Zheleznyaka Street, Krasnoyarsk, 660022-, Russian Federation
  • 2 Krasnoyarsk Regional Clinical Oncology, 16, Smolenskaya Street, Krasnoyarsk, 660133, Russian Federation
  • 3 V.M. Bekhterev National Medical Research Center of Psychiatry, Neurology of the Health Ministry of the Russian Federation, 3, Bekhterev Street, St. Petersburg, 192019-, Russian Federation
  • 4 Peoples' Friendship University of Russia, 6, Miklukho-Maklay Street, Moscow, 117198, Russian Federation
Ключевые слова
Analgesics; Antidepressants; Antimycotics; Chronic pain syndrome; Comorbidity; Drug interactions; Drug therapy; Malignant neoplasms; Opioids; Tamoxifen
Дата создания
19.07.2019
Дата изменения
19.07.2019
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/38358/