Low–grade intraepithelial cervical lesions in pregnant women with hpv and vaginal biocenotic disorders

The authors have established a relationship between intraepithelial cervical lesions and vaginal biocenotic disorders in pregnant women with human papillomavirus (HPV) infection and determined their management tactics. The HPV–positive pregnant women have a high incidence of vaginal dysbiosis (38.7%) that is, in most of them, characterized by co–infection (65%), mainly by anaerobic and aerobic infections (44.1%). High-rate HPV in the pregnant women is associated with bacterial vaginosis, mixed dysbiosis, and their recurrences and with the frequency of atypical squamous cells of undetermined significance (ASCUS) and low-grade squamous intraepithelial lesions (LSIL) in the presence of an inflammatory response. Restoring the normal microflora contributes to the disappearance of the inflammatory response and to the reduction of ASCUS. Therapy for dysbiosis does not change the rate of LSIL at 3-month follow-up. © 2018, Bionika Media Ltd.. All rights reserved.

Авторы
Издательство
ООО «Бионика Медиа»
Номер выпуска
11
Язык
Русский
Страницы
152-158
Статус
Опубликовано
Том
2018
Год
2018
Организации
  • 1 Department of Obstetrics, Gynecology and Reproductive Medicine, Faculty of Advanced Training for Medical Professionals of the Medical Institute of the Russian State University of People’s Friendship, Ministry of Education and Science, NMISE of the Ministry of Health of Russia, ul. Miklukho-Maklaya, 21, building. 3, Moscow, 117198, Russian Federation
  • 2 Department of Obstetrics and Gynecology with a course of reproductive medicine, Private Educational Institution «Academy of Medical Education named F.I. Inozemtsev», Ave, 22, letter M, St. Petersburg, Moscow, 190013, Russian Federation
Ключевые слова
Aerobic vaginitis; Bacterial vaginosis; Clindamycin/butoconazole; Dysbiosis; Human papilloma virus; Lactobacilli; Low-risk squamous intraepithelial cervical lesions; Vulvovaginal candidiasis
Дата создания
04.02.2019
Дата изменения
04.02.2019
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/36479/