A new direction in the alkylation of 5-acetyl-2-amino-6-methyl-4-phenyl-4H-pyran-3-carbonitrile with active methylene reagents

In this paper, we report a new synthesis route to 4H-pyran derivatives and a plausible reaction mechanism. The interaction of 5-acetyl-2-amino-6-methyl-4-phenyl-4H-pyran-3-carbonitrile with different active methylene reagents gives rise to the cleavage and subsequent recyclization of the pyran ring to afford the corresponding 4H-pyran derivatives. © 2018 The Chemical Society Located in Taipei & Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

Авторы
Naghiyev F.1 , Mamedov I.1 , Khrustalev V. 2 , Shixaliyev N.1 , Maharramov A.1
Издательство
Chinese Chemical Society Taiwan
Язык
Английский
Статус
Опубликовано
Год
2018
Организации
  • 1 Baku State University, Faculty of Chemistry, Baku, Azerbaijan
  • 2 People Friendship University of Russia (RUDN), Research Institute of Chemistry, Moscow, Russian Federation
Ключевые слова
active methylene compounds; benzylidenemalononitrile; Michael addition; NMR; pyran; recyclization
Дата создания
04.02.2019
Дата изменения
04.02.2019
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/36414/
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