Silylation with the Generation of a Fixed Charge for the Analysis of Alcohols by MALDI and SALDI Mass Spectrometry

Abstract: A new method of the derivatization of alcohols for their analysis by matrix-assisted laser desorption/ionization (MALDI) and surface-assisted laser desorption/ionization (SALDI) is proposed. The approach is based on the silylation of the analytes with bromomethylchlorodimethylsilane in the presence of tertiary amines to yield fixed-charge containing derivatives. The proposed method was tested using aliphatic alcohols, terpenols, and sterols. MALDI and SALDI mass spectra of all derivatives contain intense ion peaks corresponding to their cationic parts. © 2018, Pleiades Publishing, Inc.

Авторы
Zhilyaev D.I. 1 , Voskresensky L.G. 1 , Polovkov N.Y.2 , Borisov R.S. 1, 2
Редакторы
-
Издательство
-
Номер выпуска
14
Язык
Английский
Страницы
1323-1326
Статус
Опубликовано
Подразделение
-
Номер
-
Том
73
Год
2018
Организации
  • 1 People’s Friendship University of Russia, Moscow, 117198, Russian Federation
  • 2 Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, Moscow, 119991, Russian Federation
Ключевые слова
alcohols; derivatization; fixed charge; MALDI mass spectrometry; SALDI; steroids
Дата создания
04.02.2019
Дата изменения
04.02.2019
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/36206/