The paper presents a method of managing unique technological competencies as a new management object, ensuring the formation and development of an effective system for creating, producing and market launching innovative products and services based on unique technological competencies. The objectives of the proposed methodology are definition of roles and distribution of responsibility between participants of the processes of unique technological competencies management, including a new entity in the form of unique technological competencies team, the formation of new business processes, functionality, key performance indicators, employee motivation systems involved in planning and implementation of unique technological competencies commercialization measures. The paper also formulates definitions of new concepts, presents the life cycle of unique technological competencies and the relationship of unique technological competencies and centers of global technological superiority. © IAEME Publication