First synthesis and X-ray crystal structure of hexahydrobenzo[b]pyrido[3,4, 5-de]-1,6-naphthyridines
The reaction of 10-carboxamido tetrahydrobenzo[b][1,6]naphthyridines 1-3 with activated terminal alkynes in DMF/methanol resulted with the formation of hexahydrobenzo[b]pyrido[3,4,5-de]-1,6-naphthyridines 7-10- representatives of a new heterocyclic system.
Авторы
Voskressensky L.G.
1
,
Borisova T.N.
1
,
Listratova A.
1
,
Vorobiev I.V.
1
,
Aleksandrov G.G.
2
,
Varlamov A.V.
1
Издательство
HeteroCorporation
Номер выпуска
6
Язык
Английский
Страницы
1207-1210
Статус
Опубликовано
Ссылка
Том
42
Год
2005
Организации
- 1 Organic Chemistry Department, Russian Peoples Friendship University, 6, Miklukho-Maklaya St., Moscow 117198, Russian Federation
- 2 RAS Kurnakov Institute, 31, Leninsky pr., Moscow, Russian Federation
Ключевые слова
2,3,3a,4,5,6 hexahydro 1h benzo[b]pyrido[3,4,5 de][1,6]naphthyridine; 2,3,3a,4,5,6 hexahydrobenzo[b]pyrido[3,4,5 de] 1,6 naphthyridine; 4 methyl 3 (2 oxopropyl) 2,3,3a,4,5,6 hexahydro 1h benzo[b]pyrido[3,4,5 de] 1,6 naphthyridin 1 one; ethyl 2 [4 isopropyl 1 oxo 2,3,3a,4,5,6 hexahydro 1h benzo[b]pyrido[3,4,5 de][1,6]naphthyridin 3 yl]acetate; ethyl [10 bromo 4 isopropyl 1 oxo 2,3,3a,4,5,6 hexahydro 1h benzo[b]pyrido[3,4,5 de] 1,6 naphthyridin 3 yl]acetate; ethyl [4 methyl 1 oxo 2,3,3a,4,5,6 hexahydro 1h benzo[b]pyrido[3,4,5 de] 1,6 naphthyridin 3 yl]acetate; heterocyclic compound; naphthyridine derivative; unclassified drug; article; carbon nuclear magnetic resonance; chemical structure; crystal structure; electrospray mass spectrometry; proton nuclear magnetic resonance; synthesis
Дата создания
19.10.2018
Дата изменения
19.10.2018