First synthesis and X-ray crystal structure of hexahydrobenzo[b]pyrido[3,4, 5-de]-1,6-naphthyridines

The reaction of 10-carboxamido tetrahydrobenzo[b][1,6]naphthyridines 1-3 with activated terminal alkynes in DMF/methanol resulted with the formation of hexahydrobenzo[b]pyrido[3,4,5-de]-1,6-naphthyridines 7-10- representatives of a new heterocyclic system.

Редакторы
-
Издательство
HeteroCorporation
Номер выпуска
6
Язык
Английский
Страницы
1207-1210
Статус
Опубликовано
Подразделение
-
Номер
-
Том
42
Год
2005
Организации
  • 1 Organic Chemistry Department, Russian Peoples Friendship University, 6, Miklukho-Maklaya St., Moscow 117198, Russian Federation
  • 2 RAS Kurnakov Institute, 31, Leninsky pr., Moscow, Russian Federation
Ключевые слова
2,3,3a,4,5,6 hexahydro 1h benzo[b]pyrido[3,4,5 de][1,6]naphthyridine; 2,3,3a,4,5,6 hexahydrobenzo[b]pyrido[3,4,5 de] 1,6 naphthyridine; 4 methyl 3 (2 oxopropyl) 2,3,3a,4,5,6 hexahydro 1h benzo[b]pyrido[3,4,5 de] 1,6 naphthyridin 1 one; ethyl 2 [4 isopropyl 1 oxo 2,3,3a,4,5,6 hexahydro 1h benzo[b]pyrido[3,4,5 de][1,6]naphthyridin 3 yl]acetate; ethyl [10 bromo 4 isopropyl 1 oxo 2,3,3a,4,5,6 hexahydro 1h benzo[b]pyrido[3,4,5 de] 1,6 naphthyridin 3 yl]acetate; ethyl [4 methyl 1 oxo 2,3,3a,4,5,6 hexahydro 1h benzo[b]pyrido[3,4,5 de] 1,6 naphthyridin 3 yl]acetate; heterocyclic compound; naphthyridine derivative; unclassified drug; article; carbon nuclear magnetic resonance; chemical structure; crystal structure; electrospray mass spectrometry; proton nuclear magnetic resonance; synthesis
Дата создания
19.10.2018
Дата изменения
19.10.2018
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/3533/