Oxidizing reactions of azines. 8. One-reactor oxidation of 4-aryl and 4-methyl-1,2,3,6-tetrahydropyridines to 1-formylamino-substituted alkan-3-ones

One-reactor oxidation by potassium permanganate has been carried out for a series of 4-aryl- and 4-methyl-l,2,3,6-tetrahydropyridines to give 1-formylamino-substituted 3-arylpropan-3-ones and butan-3-ones. The effect has been studied of the nature of the substrate, the temperature, and interphase transfer catalysts on the yield of amino alkanone. It is proposed that the reaction proceeds through the intermediate formation of 3,4-dihydroxypiperidin-2-ones which then undergo oxidative decyclization with elimination of one carbon atom.

Редакторы
-
Издательство
Латвийский институт органического синтеза Латвийской академии наук / Springer New York Consultants Bureau
Номер выпуска
7
Язык
Английский
Страницы
844-849
Статус
Опубликовано
Подразделение
-
Номер
-
Том
37
Год
2001
Организации
  • 1 Russian People's Friendship University, Moscow 117198, Russian Federation
Ключевые слова
1-aminobutan-3-one; Oxidation of 1,2,3,6-tetrahydropyridines
Дата создания
19.10.2018
Дата изменения
19.10.2018
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/326/