Synthesis and conversions of substituted 4,5-dihydro-3H-spiro[benz-2-azepine-3,1′-cyclohexanes]

On oxidizing substituted 1,2,4,5-tetrahydro-3H-spiro[benz-2-azepine-3,1′-cyclohexanes]with potassium permanganate under phase-transfer catalysis conditions the corresponding 4,5-dihydro derivatives are formed in quantitative yield. By the action of allyl- and benzylmagnesium halides 5-methyl-4,5-dihydro-3H-spiro[benz-2-azepine-3,1′-cyclohexane] is converted into 5-methyl-1,2,4,5- tetrahydro-1-allyl(benzyl)-3H-spiro[benz-2-azepine-3,1′-cyclohexane], and by reaction with phenoxyketene and dichlorocarbene into the corresponding 2-oxoazetidino[4,1-a]- and 1,1-dichloroaziridino[3,1-a]benz-2-azepines.

Редакторы
-
Издательство
Латвийский институт органического синтеза Латвийской академии наук / Springer New York Consultants Bureau
Номер выпуска
10
Язык
Английский
Страницы
1251-1257
Статус
Опубликовано
Подразделение
-
Номер
-
Том
37
Год
2001
Организации
  • 1 Russian Peoples Friendship University, Moscow 117198, Russian Federation
Ключевые слова
Benz-2-azepines; Cyclic imines; Cycloaddition; Oxidation; Phase-transfer catalysis
Дата создания
19.10.2018
Дата изменения
19.10.2018
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/308/