Quantitative nmr spectroscopy for quality control of drugs and pharmaceuticals

Results of a comparative analysis of the use of quantitative NMR spectroscopy for the quality control of pharmaceuticals and drugs are presented. Diquertin, the active principle of which is the common flavonoid dihydroquercetin (taxifolin, 3,3′,4′,5,7-pentahydroxyflavanone), was used as an example. Quantitative 1H NMR spectroscopy can be recommended on the basis of this comparative analysis for use when it is necessary to identify all possible impurities or to confirm the absence of toxic contaminants and also for rapid analysis of samples. © 2011 Springer Science+Business Media, Inc.

Авторы
Редакторы
-
Издательство
-
Номер выпуска
3
Язык
Английский
Страницы
194-197
Статус
Опубликовано
Подразделение
-
Номер
-
Том
45
Год
2011
Организации
  • 1 People's Friendship University of Russia, Moscow, Russian Federation
Ключевые слова
dihydroquercetin; drugs; HPLC; NMR; pharmaceuticals; quality control
Дата создания
19.10.2018
Дата изменения
19.10.2018
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/2543/