Investigation of antitumor substance from Trichoderma

The effect of L-lysine-α-oxidase from Trichoderma harzianum Rifai on the functional activity of T-lymphocytes was investigated. It was shown that in a dose of 35 units/kg administered parentally the enzyme had no suppressive effect on the T-lymphocyte functional activity. An inhibitory effect of L-lysine-α-oxidase on some indices of the macrophages functional activity was observed. L-Lyzine-α-oxidase had a selective lymphotropic action and showed no mytostatic activity, which is In favour of the enzyme vs. other antitumor agents.

Авторы
Номер выпуска
9-10
Язык
Русский
Страницы
3-6
Статус
Опубликовано
Том
56
Год
2011
Организации
  • 1 N.F.Gamaleya Research Institute of Epidemiology and Microbiology, Russian Academy of Medical Sciences, Moscow, Russian Federation
  • 2 Russian University of the People's Friendship, Moscow, Russian Federation
Ключевые слова
L-lysine-α-oxidase; T-lymphocytes; Trichoderma
Дата создания
19.10.2018
Дата изменения
19.10.2018
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/2457/