Bivalirudin and percutaneous coronary interventions in patients with acute coronary syndrome: Theory and practice

This analytical paper presents the key information on the mechanism of action of a direct thrombin inhibitor – bivalirudin. The difference between bivalirudin and unfractionated or low molecular weight heparins, as well as fondaparinux, in terms of the mechanism of action, pharmacokinetics, and pharmacodynamics, is discussed. The results of clinical trials of bivalirudin and the position of this medication in the current clinical guidelines on acute coronary syndrome treatment are summarized. A detailed description of bivalirudin dosage is presented, together with the recommendations on its effective and safe use in clinical practice.

Авторы
Редакторы
-
Издательство
Silicea-Poligraf
Номер выпуска
3
Язык
Русский
Страницы
102-112
Статус
Опубликовано
Подразделение
-
DOI
-
Номер
-
Том
95
Год
2012
Организации
  • 1 City Clinical Hospital № 15, named after O. M. Filatov, Russian University of People’s Friendship, Moscow, Russian Federation
Ключевые слова
Acute coronary syndrome; Anticoagulants; Bivalirudin; Percutaneous coronary interventions
Дата создания
19.10.2018
Дата изменения
19.10.2018
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/2368/