On the reaction of fused benzodiazepines with alkynes containing electron-withdrawing groups

Fused benzodiazepines were found to react with activated alkynes to effect either vinylation of unsubstituted nitrogen atom or dealkylation of nitrogen and its further vinylation. For benzodiazepinones bearing lactam fragment, the reactions with alkynes proceed by several pathways: formation of vinyl-substituted benzodiazepines, the Stevens rearangement products, and expansion of the diazepine ring: benzodiazonine and diazecine. © 2012 Springer Science+Business Media New York.

Авторы
Редакторы
-
Издательство
-
Номер выпуска
6
Язык
Английский
Страницы
1220-1230
Статус
Опубликовано
Подразделение
-
Номер
-
Том
61
Год
2012
Организации
  • 1 Peoples' Frendship University of Russia, 6 ul. Miklukho-Maklaya, 117198 Moscow, Russian Federation
  • 2 A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 ul. Vavilova, 119991 Moscow, Russian Federation
Ключевые слова
benzopyrrolo-1,4-diazonine; octahydrobenzo1,7-diazecine; tandem cleavage; tandem expansion; tetrahydrobenzo-1,4-diazepines; the Stevens rearangement
Дата создания
19.10.2018
Дата изменения
19.10.2018
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/2310/