24-Acetyl-8,11,14-trioxa-24,27-diazapentacyclo[19.5.1.122,26. 02,7.015,20]octacosa-2,4,6,15(20),16,18-hexaen-28-one

The title compound, C25H28N2O5, is a product of the Petrenko-Kritchenko condensation of N-acetyl-piperidone with 1,5-bis(2-formylphenoxy)-3-oxapentane and ammonium acetate. The molecule comprises a fused pentacyclic system containing an aza-14-crown-3-ether macrocycle, two piperidone and two benzene rings. The aza-14-crown-3-ether ring adopts a bowl conformation. The dihedral angle between the benzene rings fused to the aza-14-crown-4-ether unit is 70.18 (4)°. The central piperidone ring has a boat conformation, whereas the terminal piperidone ring adopts a chair conformation. The conformation of the central piperidone ring is determined by two intramolecular N - H⋯O hydrogen bonds. In the crystal, molecules are linked by weak C - H⋯O interactions into chains along [010]. © 2012 International Union of Crystallography.