Synthesis of epoxyisoindolo[1,2-a]isoquinolinium salts by an intramolecular [2+4] cycloaddition reaction in 2-allyl-1-furylisoquinolinium halides

We examined the tandem alkylation/[2+4] cycloaddition of 1-(2-furyl)-3,4-dihydroisoquinolines by various allyl halides. It was found that the process occurred through the intermediate formation of 2-allyl-1-furyl-3,4- dihydroisoquinolinium salts with a subsequent intramolecular exo addition of the allyl fragment to the furan ring. The adducts obtained were structural analogs of the isoindolo-[1,2-a]isoquinoline alkaloids jamtine and hirsutine. © 2013 Springer Science+Business Media New York.

Авторы
Zubkov F.I. 1 , Zaytsev V.P. 1 , Obushak M.D.2 , Ershova Y.D. 1 , Mertsalov D.F. 1 , Sorokina E.A. 1 , Nikitina E.V. 1 , Gorak Y.I.2 , Lytvyn R.Z.2 , Varlamov A.V. 1
Издательство
Латвийский институт органического синтеза Латвийской академии наук / Springer New York Consultants Bureau
Номер выпуска
5
Язык
Английский
Страницы
746-759
Статус
Опубликовано
Том
49
Год
2013
Организации
  • 1 Peoples' Friendship University of Russia, 6 Miklukho-Maklaya St., Moscow 117198, Russian Federation
  • 2 Ivan Franko Lviv National University, 6 Kyril and Mefody St., Lviv 79005, Ukraine
Ключевые слова
alkaloids; allyl halides; furan; intramolecular [2+4] cycloaddition; isoindolo[1,2-a]isoquinolines
Дата создания
19.10.2018
Дата изменения
19.10.2018
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/2031/
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