Synthesis, Molecular Docking, and Biological Activity of New EGFR-Targeted Photosensitizers Based on Cationic Porphyrins Encapsulated into Pluronic F127 Micelles

Bortnevskaya Yulia S.¹ , Zakharov Nikita S.¹ , Senkov Vadim S.¹ , Gradova Margarita A.² , Karpechenko Natalia Yu.^{1, 3, 4} , Nikolskaya Elena D.⁵ , Mollaeva Mariia R.⁵ , Yabbarov Nikita G.⁵ , Novikov Alexander S. ^{6, 7} , Bragina Natal’ya A.¹ , Zhdanova Kseniya A.¹

Molecular Pharmaceutics

American Chemical Society

Английский

Опубликовано

Внешняя ссылка

10.1021/ACS.MOLPHARMACEUT.5C00247

2025

• ¹ MIREA - Russian Technological University, Institute of Fine Chemical Technology, Vernadsky pr., 86, 119571 Moscow, Russian Federation
• ² N.N. Semenov Federal Research Center for Chemical Physics, Russian Academy of Sciences, Kosygin Street 4, 119991 Moscow, Russia
• ³ N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia, Kashirskoe Highway, 24, 115522 Moscow, Russia
• ⁴ Pirogov National Research Medical University, Ministry of Health of Russia, 1 Ostrovityanova St., 117997 Moscow, Russia
• ⁵ Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Kosygina Street, 4, 119334 Moscow, Russia
• ⁶ Institute of Chemistry, Saint Petersburg State University, Universitetskaya nab. 7−9, 199034 Saint Petersburg, Russia
• ⁷ Research Institute of Chemistry, Peoples’ Friendship University of Russia (RUDN University), Miklukho-Maklaya Street, 6, 117198 Moscow, Russia