International Journal of Environmental Research. Том 18. 2024.
Preparation of Tritium Labeled Dexamethasone Phosphate and Its Application to Assess the Affinity of Ligands for Glucocorticoid Receptors
Abstract: The possibility of introducing tritium into dexamethasone and dexamethasone phosphate using the thermal activation method was demonstrated. The affinity of ligands for glucocorticoid receptors has been successfully assessed using labeled compounds. © Pleiades Publishing, Ltd. 2024.
Авторы
Badun G.A. , Zhidkova E.M. , Chernysheva M.G. , Enikeev A.D. , Yakubovskaya M.G. , Lesovaya E.A.
Журнал
Номер выпуска
4
Язык
Английский
Страницы
514-521
Статус
Опубликовано
Ссылка
Том
66
Год
2024
Организации
- 1 Faculty of Chemistry, Moscow State University, Moscow, 119991, Russian Federation
- 2 Blokhin Russian Cancer Research Center, Ministry of Health of Russia, Kashirskoe shosse 24, Moscow, 115478, Russian Federation
- 3 Friendship University of Russia, ul. Miklukho-Maklaya 6, Moscow, 117198, Russian Federation
- 4 Pavlov Ryazan State Medical University, Ministry of Health of Russia, Vysokovol’tnaya ul. 9, Ryazan, 390026, Russian Federation
Ключевые слова
glucocorticoid; glucocorticoid receptor; radioligand binding assay; selective glucocorticoid receptor agonists; tritium
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Другие записи
Proceedings of the Steklov Institute of Mathematics. Том 325. 2024. С. S168-S178