Advanced Taste-Masking Methods of Solid Dosage Forms

One of the main problems in medical practice is the lack of patient adherence to treatment, which is often attributed to the bitterness or sourness of medicines causing discomfort and an aversion during administration, especially in children. Therefore, masking an unpleasant taste is one of the goals of pharmaceutical development. Currently, there are various approaches to improving the taste of oral dosage forms containing bitter or excessively sour pharmaceutical substances. This review covers some of these approaches and their advantages and disadvantages and provides relevant examples of the possible use of each of them. © 2023, Springer Science+Business Media, LLC, part of Springer Nature.

Авторы
Bueva V.V. , Blynskaja E.V. , Alekseev K.V. , Minaev S.V. , Eremin V.A.
Номер выпуска
9
Язык
Английский
Страницы
1494-1498
Статус
Опубликовано
Том
57
Год
2023
Организации
  • 1 Research Zakusov Institute of Pharmacology, 8 Baltiiskaya St, Moscow, 125315, Russian Federation
  • 2 People’s Friendship University of Russia, Institute of Biochemical Technology and Nanotechnology, 10 Miklukho-Maklaya St, Moscow, 117198, Russian Federation
Ключевые слова
film coatings; flavorings; multidose systems; sweeteners; taste masking
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