Dynamics of delay epidemic model with periodic transmission rate

We introduce novel epidemic models with single and two strains described by systems of delay differential equations with a periodic time-dependent disease transmission rate, and based on the number of newly infected individuals. Transitions between infected, recovered, and returning to susceptible compartments due to waning immunity are determined by the accompanying time delays. Positiveness, existence and uniqueness of solutions are demonstrated with the help of fixed point theory. Reducing delay differential equations to integral equations facilitates determining the analytical estimation of the equilibrium solutions. When there are two strains, they compete with each other, and the strain with a larger basic reproduction number dominates in the population. However, both strains coexist, and the magnitudes of epidemic outbreaks are governed by the basic reproduction numbers. The results of this work are verified through comparison with seasonal influenza data. © 2024 Elsevier Inc.

Авторы
Saade M. , Ghosh S. , Banerjee M. , Volpert V.
Издательство
Elsevier Inc.
Язык
Английский
Статус
Опубликовано
Номер
115802
Том
138
Год
2025
Организации
  • 1 Peoples Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St, Moscow, 117198, Russian Federation
  • 2 Department of Mathematics, IIT Bombay, Powai, Mumbai, 400076, India
  • 3 Department of Mathematics and Statistics, IIT Kanpur, Kanpur, 208016, India
  • 4 Institut Camille Jordan, UMR 5208 CNRS, University Lyon 1, Villeurbanne, Lyon, 69622, France
Ключевые слова
Delay epidemic model; Immunity waning; Periodic time-dependent disease transmission rate; Re-infection; Two strains
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