Blood Substitutes with Gas Transfer Function

The review presents the results of the blood substitute development based on perfluororganic compounds (PFC). The limitations of PFC due to which their further development was suspended are described. The presented data allows us to imagine a possible way to create optimal drugs based on PFC. Chemically inactive perfluorocomponents should be used — perfluorinated hydrocarbons and tertiary perfluorinated amines. However, in order to emulsify and stabilize the emulsion, other types of effective and chemically indifferent surfactants that do not interact with oxygen and other components of the drug are needed. © Springer Science+Business Media, LLC, part of Springer Nature 2024.

Авторы
Khromov A.V. , Novikov O.O. , Novikova E.O.
Издательство
New York Consultants BureauSpringer / Автономная некоммерческая организация Издательство Российской академии медицинских наук
Номер выпуска
6
Язык
Английский
Страницы
709-715
Статус
Опубликовано
Том
176
Год
2024
Организации
  • 1 Peoples’ Friendship University of Russia (RUDN University), Moscow, Russian Federation
  • 2 Branch of S. M. Kirov Military Medical Academy in Moscow, Moscow, Russian Federation
Ключевые слова
blood substitutes; perfluororganic compounds; limitations of existing developments; development prospects of the direction
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