For a long time orthodontists has been developing primers and bonds with improved adhesive properties for fixing metal braces to the teeth enamel, which is especially important for lateral teeth. The aim of the study was to compare the results of the shear strength of adhesion between a domestic adhesive system of the V generation and a foreign analogue in laboratory conditions. Materials and methods. The study was carried out using 20 samples of extracted molars of the upper and lower jaws, which were immersed in blocks of acrylic plastic. All samples were divided into two groups: in the group I the fixation of metal braces to the teeth enamel was carried out using a domestic adhesive system Compofix (ortho) (VladMiVa, Russia); in the group II the fixation of metal braces to the teeth enamel was performed using a foreign analogue Enlight (Ormco, USA). Results. In the group I the value of shear adhesion was 13.21±1.11 MPa, while in the group II — 13.39±1.23 MPa. The average value of the adhesive remant index to the bracket surface was 18±3% in the group I and 15±3% in the group II. Conclusion. The results of the study showed that the domestic adhesive system of the V generation is not inferior in its properties to a foreign analogue and is recommended for use in the clinical practice in orthodontics. © The Author(s) 2023.