Chromatic Differentiation of Functional Mappings of the Composition of Nucleic Acids

Color visualization of the DNA of diverse living beings can help in the exploration of the issue of chromatic differentiation of functional mappings of the nucleotide composition of DNA molecules. By “chromatic differentiation”, we mean the coloring of these mappings. Algorithms for coloring genetic representations improve the perception of complex genetic information using color. Methodologically, to build the chromatic differentiation of functional mappings of the nucleotide composition of DNA, we employed the system of nucleotide Walsh functions and the Chaos Game Representation (CGR) algorithm. The authors compared these two approaches and proposed a modified CGR algorithm. The work presents various algorithms of chromatic differentiation based on the nucleotide Walsh functions at a specific location of the fragment in the nucleotide chain and on the frequencies of those fragments. The results of the analysis provide examples of chromatic differentiation in a variety of parametric spaces. The paper describes various approaches to coloring and video animation of DNA molecules in their chromatically differentiated spans of physicochemical parameters. © 2023 by the authors.

Авторы
Stepanyan I.V. , Lednev M.Y.
Журнал
Издательство
MDPI AG
Номер выпуска
4
Язык
Английский
Статус
Опубликовано
Номер
942
Том
15
Год
2023
Организации
  • 1 Mechanical Engineering Research Institute of the Russian Academy of Sciences (IMASH RAN), 4, M. Kharitonyevskiy Pereulok, Moscow, 101990, Russian Federation
  • 2 Peoples’ Friendship University of Russia, RUDN University, 6, Miklukho-Maklaya Street, Moscow, 117198, Russian Federation
Ключевые слова
chromatic differentiation; coloring; DNA; nucleic acids; nucleotide composition; RNA; visualization methods
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