Studies on the role of non-coding RNAs in controlling the activity of T cells in asthma

Bronchial asthma, commonly known as asthma, is a chronic inflammatory disease characterized by airway inflammation, increased responsiveness and changes in airway structure. T cells, particularly T helper cells, play a crucial role in the disease. Non-coding RNAs, which are RNAs that do not code for proteins, mainly include microRNAs, long non-coding RNAs, and circular RNAs, play a role in regulating various biological processes. Studies have shown that non-coding RNAs have an important role in the activation and transformation of T cells and other biological processes in asthma. The specific mechanisms and clinical applications are worth further examination. This article reviews the recent research on the role of microRNAs, long non-coding RNAs and circular RNAs in T cells in asthma. © 2023 The Authors

Авторы
Sufianov A. , Bessonova M. , Begliarzade S. , Kudriashov V. , Danilov A. , Ilyasova T. , Yaolou W. , Nafikova R. , Beylerli O.
Издательство
KeAi Communications Co.
Номер выпуска
2
Язык
Английский
Страницы
211-217
Статус
Опубликовано
Том
8
Год
2023
Организации
  • 1 Educational and Scientific Institute of Neurosurgery, Рeoples’ Friendship University of Russia (RUDN University), Moscow, Russian Federation
  • 2 Department of Neurosurgery, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation
  • 3 Tyumen Cardiology Research Center, Tomsk National Research Medical Center, Russian Academy of Science, Tomsk, Russian Federation
  • 4 Republican Clinical Perinatal Center, Republic of Bashkortostan, Ufa, 450106, Russian Federation
  • 5 Gastric Cancer Center, West China Hospital of Sichuan University, China
  • 6 Department of Clinical Pharmacology, Smolensk State Medical University, Smolensk, Russian Federation
  • 7 Department of Internal Diseases, Bashkir State Medical University, Republic of Bashkortostan, Ufa, 450008, Russian Federation
  • 8 Harbin Medical University, 157 Baojian Rd, Nangang, Harbin, 150088, Heilongjiang, China
  • 9 Department of Pulmonary and Critical care, Northwestern University, Chicago, United States
Ключевые слова
Asthma; Circular RNAs; Long non-coding RNAs; microRNAs; Non-coding RNAs; T cells
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