Since centuries women have been target of family planning measure and medicines. But chemical contraceptives are inherently unreliable and interfere with delicate and complex immunologicalreproductive system of women with high risk. This provided an opportunity to the research scholars to explore herbal contraceptive medicine. The concept of contraceptive is not a new to Ayurveda. Various contraceptives are mentioned in classical Ayurvedic texts. Such as 1) Pippali (Piper longum), Vidanga (Emblicaribes) and Tankana (SodiiBiboras). 2) Talisapatra (Taxus baccata) and Gairika (Hematite) with cold water and 3) Kanji (sour gruel) Bhavita(triturated) Japakusuma (Hibiscus rosa sinensis). The herbo mineral combination of Pippali (Piper longum), Vidanga (Emblicaribes) and Tankana (SodiiBiboras) was subjected for anti-implantation activity on albino rats by Choudhary and Khanna's method. Significant difference was noted in number of implantations, in weight of uterus and ovary in study group compared with standard group. Histological reports on isolated ovary reveals that study drug combination was suppressed the maturation of graffian follicle. Pippali, Vidanga and Tankana drug combination shown significant anti-implantation activity in albino rats and given further scope for clinical study which may contribute a better contraceptive medicine to female generation under national mainstream of health programme. © RJPT All right reserved.