Functional outcome at 6 months of surgical traumatic brain injury: A single Caribbean Center pilot study; [ФункЦиональные исХоды Хирургического лечениЯ паЦиентов с черепно-мозговой травмой через 6 месЯЦев после операЦии: карибское одноЦентровое пилотное исследование]

Background. This is the first prospective study that evaluates the functional outcome after a surgical procedure sec- ondary to a traumatic brain injury, in a single center, in Dominican Republic. Aim. To determine the functional status of surgically treated patients 6 months post-trauma, the relative risk of poor prognosis and association of functional status with the predictive variables of the International Mission for Prognosis and Analysis of Clinical Trials in traumatic brain injury. Materials and methods. A prospective, longitudinal study was conducted in a cohort of 22 patients surgically treated for a traumatic intracranial injury at Dr. Ney Arias Lora Traumatology Hospital in Dominican Republic. We applied the International Mission for Prognosis and Analysis of Clinical Trials calculator, (pupillary response, hemoglobin, hypoxia, age, motor response, computed tomography lesion, hypotension, etc.) prior to surgery and the Extended Glasgow Outcome Scale 6 month after surgery to determine the functional outcome. The International Mission for Prognosis and Analysis of Clinical Trials form was modified by adding preoperative glucocorticosteroids and rehabilitation therapy. The SPSS database (15.0 version, Chicago Il.) was used. Central tendency measures and Fisher's test were applied. Thus, p ≤0.05 with a 95 % confidence interval was considered statistically significant. Results. The predictive variables associated with a poor prognosis were motor response (p = 0.01), hypoxia and hypo- tension (p = 0.05). Alterations in motor response was associated with increased morbidity and mortality (RR: 10; 95 % CI: 3-22). Normal flexion was found in all patients with good recovery (p = 0.04). Conclusion. As a result, 67 % of patients had a good functional result (moderate disability and good recovery). Mor- tality was 23 %. Preoperative motor response is a powerful prognostic factor in traumatic brain injury. © 2022 Russian Journal of Neurosurgery. All rights reserved.

Авторы
De Jesus Encarnacion M. , Baez I.P. , Paulino J. , Castillo R.E.B. , Nurmukhametov R. , Efe I.E.
Издательство
Автономная некоммерческая организация по изданию журнала "Нейрохирургия"
Номер выпуска
3
Язык
Английский
Страницы
32-36
Статус
Опубликовано
Том
24
Год
2022
Организации
  • 1 RUDN University, 6 Miklukho-Maklaya St., Moscow, 117198, Russian Federation
  • 2 Hospital Dr. Alejandro Cabral, Diego De Velasquez, San Juan de la Maguana, Dominican Republic
  • 3 Dr. Ney Arias Lora Traumatology Hospital, G4W8+W92 Charles de Gaulle Avе., Santo Domingo, Dominican Republic
  • 4 Charite - Berlin University of Medicine, 1 Chariteplatz, Berlin, 10117, Germany
Ключевые слова
Extended Glasgow Outcome Scale; functional status; IMPACT; International Mission for Prognosis and Analysis of Clinical Trials; surgical traumatic brain injury; TBI
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