The article describes the gas chemistry research carried out in a geodynamic zone detected by the geodynamic zoning in the south of the Moscow Region in 2002. The understudied impact of geodynamic zones on the health and environment actualizes studies into reflections of geodynamic zones (block joints) in the near-surface atmospheric gas fields. To that effect, in May 2022, the gas chemistry survey was carried out along the route 1.5 km long from Sotnikovo settlement northward across the trend of the geodynamic zone. It is supposed that emission of deep-earth gases to ground surface is more intense in geodynamically active zones which are the highly permeable areas in the earth crust. The experimental research used the micro geodynamic mapping procedure earlier developed and approved in the course of hydrogeological and geological engineering. The interpretation of the results allows drawing a conclusion that that the methods of geodynamic zoning and micro geodynamic mapping can effectively complement each other in the environmental and geodynamic safety analyses and in studying deep-earth gas migration to ground surface. Moreover, it is possible to combine these methods in handling of the environmental and geodynamic safety issues in different-purpose areas. © 2022 Publishing house Mining book. All rights reserved.