Alterations in the myocardial ultrastructure of the perfused rabbit heart

The ultrastructure of rabbit heart left ventricle isolated according to Langendorf was examined under different conditions: in intact animals, during ligation of the coronary artery, and hypoxic heart perfusion. The intact perfused heart showed unremarkable exo- and intracellular edema and moderate swelling of the mitochondria. During hypoxic perfusion, marked swelling and destruction of the mitochondria were noted. During ligation of the coronary artery, the heart was characterized by a high degree of mitochondrial heterogenicity. The correlation of the data obtained allowed one to reveal the myocardial adaptive-accommodative mechanism, (intermittent mitochondrial activity) that makes it possible to maintain heart bioenergetics during coronary artery occlusion at a permanently high level.

Редакторы
-
Издательство
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Номер выпуска
10
Язык
Русский
Страницы
496-499
Статус
Опубликовано
Подразделение
-
DOI
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Номер
-
Том
98
Год
1984
Организации
  • 1 Patrice Lumumba University of Peoples' Friendship, Moscow
Ключевые слова
animal cell; electron microscopy; etiology; heart; heart infarction; heart muscle perfusion; mitochondrion; nonhuman; rabbit; ultrastructure; animal; anoxia; article; comparative study; heart mitochondrion; heart muscle; heart ventricle; methodology; mitochondrion swelling; pathology; perfusion; Animalia; Oryctolagus cuniculus; Animal; Anoxia; Comparative Study; English Abstract; Heart Ventricle; Microscopy, Electron; Mitochondria, Heart; Mitochondrial Swelling; Myocardium; Perfusion; Rabbits
Дата создания
19.10.2018
Дата изменения
19.10.2018
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/1399/