The objects of study were microorganisms, isolated from pathological material of chicken breeds "RoSS 208" and "Luong Phuong"; ducklings breeds "C. V. super M" and a "Khaki Campbell"; quails breed "Coturnix". In 499 samples of the birds material we discovered 153 microorganisms cultures of the genus Salmonella, which were 30.66 % of the total number of selected microorganisms cultures, including S. typhimurium - 60 (39.22 %) strains; S. albany - 32 (of 20.92 %); S. enteritidis - 20 (13.07 %); S. hadar - 9 (5.88%); S. agona and S. thompson - 5 (3.27 %); S. indiana - 4 (2.61 %); S. heidelberg, S. mbandaka and S. shalkwijk - 3 (1.96 %); S. give - 2 (1.31 %); S. derby and S. havana - 1 (0.65 %); other serovar - 5 (3.27 %). It was found that 70.0 % of the studied strains were sensitive to drugs of the fluoroquinolone group (nalidixic acid, norfloxacin, ciprofloxacin, enrofloxacin), 66.67 % - cephalosporins (ceftazidim). 83.33 % of strains were resistant to tetracycline drugs (tetracycline); 63.33 % - β-lactams (ampicillin); 56.67 % - aminoglycosides (gentamicin, kanamycin, streptomycin); 46.67 % - sulfonamides (trimethoprim). The minimum inhibitory concentration ("MIC") were established at the intersection of the growth suppression zone and the test strip "E-test": ampicillin-512 μg/ml; tetracycline - 64 μg/ml; gentamicin - 2 μg/ml; ciprofloxacin - 1 μg/ml; norfloxacin - 0.38 μg/ml and ceftazidim - 0.19 μg/ml. The amplitude values ranged from 0.019 μg/ml to 512 μg/ml. © Advanced Scientific Research. All rights reserved.