Effects of cilazapril on cardiac structure and function in hypertension

Peripheral vascular resistance, arterial blood pressure, and left ventricular hypertrophy (LVH) are closely related. In systemic hypertension, hemodynamic changes in systolic and diastolic function accompany LVH. Both of these cardiac functions are detected with echocardiography and were measured during this study in 23 essential hypertension patients treated with 2.5–5 mg of cilazapril daily for 6 months. Reduction in left ventricular mass was accompanied by an improvement in early diastolic filling pattern. This change in cardiac performance with cilazapril vasodilator monotherapy was characterized by a significant improvement in isovolumic relaxation time and normalized left ventricular early/atrial filling ratio. © 1994 Raven Press. Ltd., New York.

Language
English
Pages
S70-S72
Status
Published
Volume
24
Year
1994
Organizations
  • 1 Department of Internal Medicine and Clinical Pharmacology, Russian Peoples Friendship University, Moscow, Russian Federation
Keywords
Antihypertension therapy with cilazapril; Cardiac function; Hypertension; Left ventricular hypertrophy
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/964/