Clinical significance of hemostatic disorders in infectious endocarditis

Aim. Study of blood clotting to evaluate hemostatic disorders in infectious endocarditis (IE). Materials and methods. The trial included 124 patients,vith IE (61 males and 63 females aged 15-70 years). Primary and secondary IE was in 38 and 62% of patients, respectively. Results, Clinically evident hemostatic disorders were observed in 93(74.2%) cases. They manifested as intravascular platelet activation with development of hypercoagulatory status and chronic DIC-syndrome. Conclusion. A differentiated approach is advisable to correction of thrombotic disorders in IE basing on the severity of blood coagulation impairment.