Pyridoxine metabolism in patients with skin leishmaniasis in Libya

Epidemiological screening carried out in Libya revealed 1539 patients with zoonotic skin leishmaniasis who were treated, with consideration for the indications, by glucantine, lincocine, vilbramycin, keflex, amoxil, tigason, nisoral, and levamisole. Good results were attained in 1237 (80.3%) patients. In 302 (19.7%) patients the treatment was ineffective; laboratory tests revealed in their blood a marked deficit of pyridoxine. An extra course of therapy of these patients with vitamin B6 preparations pyriditol and pyridoxal phosphate was conducive to complete cure of these patients and recovery of normal pyridoxine level in the blood.

Authors
Khaddad S.M.1 , Tishchenko L.D.1 , Mushara Kh.A. , Tishchenko A.L.1
Journal
Vestnik Dermatologii i Venerologii
Number of issue
6
Language
Russian
Pages
29-31
Status
Published
Link
External link
Volume
70
Year
1994
Organizations
  • 1 Kafedra Kozhnykh i Vener. Boleznej, Ross. Universitet Druzhby Narodov, Moskva, Russian Federation
Keywords
amoxicillin; cefalexin; doxycycline; etretinate; ketoconazole; levamisole; lincomycin; meglumine antimonate; pyridoxal 5 phosphate; pyridoxine; pyritinol; article; human; leishmaniasis; libyan arab jamahiriya; major clinical study; skin infection; vitamin deficiency
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/924/
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