Synthesis of functionalized tetrahydropyridones by the tandem Knoevenagel—Michael—intramolecular ammonolysis—alkylation reaction

The tandem Knoevenagel—Michael—intramolecular ammonolysis—alkylation reaction was used to synthesize functionalized tetrahydropyridones. The molecular and crystal structures of four pyridone derivatives were studied by X-ray diffraction. © 2021, Springer Science+Business Media LLC.

Authors
Dyachenko I.V. 1 , Dyachenko V.D. 1 , Dorovatovskii P.V. 2 , Khrustalev V.N. 3, 4 , Nenajdenko V.G. 5
Journal
Russian Chemical Bulletin
Issue number
11
Language
English
Pages
2145-2155
State
Published
Link
External link
DOI
10.1007/S11172-021-3326-9
Volume
70
Year
2021
Organizations
  • 1 Lugansk State Pedagogical University, 2 ul. Oboronnaya, Lugansk, 91011, Ukraine
  • 2 National Research Center “Kurchatov Institute”, 1 ul. Akad. Kurchatova, Moscow, 123182, Russian Federation
  • 3 Peoples’ Friendship University of Russia (RUDN University), 6 ul. Miklukho-Maklaya, Moscow, 117198, Russian Federation
  • 4 N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., Moscow, 119991, Russian Federation
  • 5 Lomonosov Moscow State University, 1 Leninskie Gory, Moscow, 119991, Russian Federation
Keywords
alkylation; functionalized tetrahydropyridones; intramolecular ammonolysis; Knoevenagel reaction; Michael reaction; X-ray diffraction
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