The research goal of this scientific work is to identify trends related to the use of digital technologies in the process of resolving disputes between business entities. Trade cooperation between countries is the first to feel the changes associated with the transition to an electronic form of interaction, and therefore needs a clear and predictable mechanism for protecting the interests of the subjects involved in this process. It is proved that: 1) legal regulation of the use of technical means in methods of protection of rights and legitimate interests, often does not correspond to modern realities; 2) it is necessary to regulate the process of dispute resolution using digital technologies by law; 3) the creation of a single information space where market participants would be connected, as well as mechanisms for resolving commercial and other disputes related to business activities, can significantly increase the growth of economic cooperation; 4) it is necessary to create a transparent method for resolving commercial disputes; 5) the introduction of new modern technologies increases the efficiency of the dispute resolution process; 6) the global trend in reforming the dispute resolution process is the transition to the use of artificial intelligence, as well as” smart “ technologies; 7) there is a gravitation not only to online (Internet, electronic) alternative methods of dispute resolution, but online (Internet, electronic) judicial form of legal protection. International trade cooperation within the framework of the associations of States of the EAEU, BRICS, APEC, and SCO countries is aimed at moving to advanced digital, intelligent manufacturing technologies, robotic systems, new materials and methods of construction, creating systems for processing large amounts of data, and implementing artificial intelligence. For successful economic cooperation, it is necessary to create a single digital space, however, this goal affects not only the private interests of investors, but also the public interests of these States, so achieving a balance is extremely difficult. Close economic cooperation should also be provided with modern innovative mechanisms for dispute resolution. © 2022 by Information Age Publishing. All rights reserved.