Improved Method for Preparation of 3-(1H-Indol-3-yl)benzofuran-2(3H)-ones

3-(1H-Indol-3-yl)benzofuran-2(3H)-ones were efficiently accessed via polyphosphoric acid-mediated condensation of 3-(2-nitrovinyl)-1H-indoles with phenols. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.

Authors
Grishin I.Yu. 1 , Arutiunov N.A. 1 , Aksenov D.A. 1 , Aksenov N.A. 1 , Aksenov A.V. 1 , Gasanova A.Z. 1 , Sorokina E.A. 2 , Lower C. 3 , Rubin M. 1, 3
Journal
Molecules
Publisher
MDPI AG
Issue number
6
Language
English
State
Published
Link
External link
DOI
10.3390/MOLECULES27061902
Number
1902
Volume
27
Year
2022
Organizations
  • 1 Department of Chemistry and Pharmacy, North Caucasus Federal University, 1a Pushkin St., Stavropol, 355017, Russian Federation
  • 2 Organic Chemistry Department, Peoples’ Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St., Moscow, 117198, Russian Federation
  • 3 Department of Chemistry, University of Kansas, 1567 Irving Hill Road, Lawrence, KS 66045, United States
Keywords
Brønsted acid catalysis; cascade transformations; indoles; nitroalkanes; rearrangements
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