Managing Wound Healing with a High-Risk Patient: A Case Report

Wound healing is a complex, multi-step process. This process begins immediately after skin damage. The outcome of wound healing depends on the quality of each stage of this process: a normal or pathological scar. Violation of wound healing entails a decrease in the function of scar tissue as well as aesthetic dissatisfaction with the patient. This problem is especially important in aesthetic surgery. Patients who have come for beauty feel frustration, obtaining pathological scars. We have been dealing with the problem of wound healing after plastic surgery for about 10 years. Our approach includes the assessment of the risk of pathological wound healing and the treatment of high-risk patients. The risk assessment includes historical data on wound healing, signs of connective tissue dysfunction (especially patients with connective tissue dysplasia), and genetic polymorphisms of genes responsible for the structure of the components of the extracellular matrix of the skin. In the future, patients with a high risk of pathological scarring can be prescribed treatment after surgery. This article presents a clinical case in which we demonstrate our approach. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.

Authors
Potekaev N.N. 1 , Borzykh O.B.2 , Medvedev G.V.3 , Petrova M.M.2 , Karpova E.I.1 , Zatolokina M.A.4 , Al-Zamil M. 5 , Demina O.M.1 , Narodova E.A.2 , Shnayder N.A. 2, 6
Journal
Publisher
MDPI
Number of issue
2
Language
English
Status
Published
Number
28
Volume
9
Year
2022
Organizations
  • 1 Department of Skin Disease and Cosmetology, Pirogov Russian National Research Medical University, Moscow, 117997, Russian Federation
  • 2 Department of Shared Core Facilities “Molecular and Cell Technologies”, Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, 660022, Russian Federation
  • 3 Department of Hand Surgery with Microsurgical Equipment, R. R. Vreden National Medical Research Centre for Traumatology and Orthopedics, Saint Petersburg, 195427, Russian Federation
  • 4 Department of Histology, Embryology, Cytology, Medical Faculty, Kursk State Medical University, Kursk, 305014, Russian Federation
  • 5 Department of Physiotherapy, Faculty of Continuing Medical Education, Peoples’ Friendship, University of Russia, Moscow, 117198, Russian Federation
  • 6 Institute of Personalized Psychiatry and Neurology, Shared Core Facilities, V. M. Bekhterev National Medical Research Centre for Psychiatry and Neurology, Saint Petersburg, 192019, Russian Federation
Keywords
Plastic surgery; Rejuvenation; Scars; Wound healing
Date of creation
06.07.2022
Date of change
06.07.2022
Short link
https://repository.rudn.ru/en/records/article/record/83729/
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