Spermatogenesis recovery following allogeneic transplantation of undifferentiated Sertoli cells in experimental model of bilateral abdominal cryptorchidism

This study explores the effect of transplantation of undifferentiated Sertoli cells in the testicular tissue of an experimental animal model of bilateral abdominal cryptorchidism. Effectiveness of undifferentiated Sertoli cell transplantation was assessed after 1 and 3 months after injection. Partial restoration of seminiferous tubules was found to occur after transplantation. In a third of them germ cells of all stages of the differentiation were discovered while they were not found in the control group.

Authors
Kulibin A.Y.1 , Malolina E.A.1, 2 , Jacyk S.P.3 , Zhamynchiev J.K.3 , Kuzin G.V. 4
Number of issue
6
Language
Russian
Pages
74-81
Status
Published
Year
2015
Organizations
  • 1 Koltzov Institute of Developmental Biology of RAS
  • 2 Gamaleya Scientific Research Institute of Epidemiology and Microbiology of Minzdrav of Russia
  • 3 Department of Reproductive Health of Scientific Center of Children's Health
  • 4 Faculty of Medicine of the Peoples Friendship University of Russia
Keywords
cryptorchidism; pediatric uro-andrology; transplantation; undifferentiated Sertoli cells
Date of creation
06.07.2022
Date of change
06.07.2022
Short link
https://repository.rudn.ru/en/records/article/record/83483/
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