Cleavage of some annulated tetrahydropyridines under the action of dimethyl acetylene dicarboxylate in protic solvents. New practical route to substituted pyrroles and indoles

Tetrahydropyrrolo[3,2-c]pyridines and tetrahydropyrido[4,3-b]indoles undergo piperidine ring opening under the action of dimethyl acetylene dicarboxylate in alcohols or in aqueous dioxane, providing β -(alk)oxy-substituted pyrroles (indoles) in moderate to high yields.

Editors
-
Conference proceedings
Publisher
-
Number of issue
3-4
Language
English
Pages
207-212
Status
Published
Department
-
Link
-
Number
-
Volume
6
Year
2003
Organizations
  • 1 Organic Chemistry Department, Russ. Peoples Friendship University, 6, Miklukho-Maklaya St., Moscow, 117198, Russian Federation
Keywords
Cleavage; Indole; Pyridines; Pyrrole; Tandem reactions
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/8/