Assessment of diagnostic efficiency of digital breast tomosynthesis in diagnostics of breast diseases [ОЦЕНКА ДИАГНОСТИЧЕСКОЙ ЭФФЕКТИВНОСТИ РЕНТГЕНОЛОГИЧЕСКОГО ТОМОСИНТЕЗА ПРИ ЗАБОЛЕВАНИЯХ МОЛОЧНОЙ ЖЕЛЕЗЫ]

purpose. To define the diagnostic efficiency and the main advantages of digital breast tomosynthesis. Material and methods. For achievement of the goal during the period from July, 2013 to September, 2017 examinations in 150 patients aged from 29 to 79 years (middle age – 58.4 ±11.3 years) were made in Gazprom clinic and MNIOI of P.A. Herzen using digital X-ray equipment: "GIOTTO Image TOMO", GIOTTO Image SDL (IMS, Italy) and "Senograph Essential" (GE Healthcare, the USA). The diagnostic complex included: clinical examination, mammography in two projections, digital breast tomosynthesis in a necessary projection depending on characteristics and localization of the pathology, breast ultrasonography. The fine-needle aspiration biopsy and core- biopsy under control of a method of the best visualization was applied for morphological verification. Results. The sensitivity of digital breast tomosynthesis in detecting of breast abnormalities was 92.6%, 95% of CI (82.4%-97.1%), specificity – 88.5%, 95% of CI (80.6%-93.5%), accuracy – 90.0%, 95%CI (83.8%-94.0%), PPV – 82.0%, 95% of CI (70.5%-89.6%), NPV – 95.5%, 95% of CI (89.0%-98.2%). The sensitivity of mammography in detecting of breast abnormalities was 79.6%, 95% of CI (67.1%-88.23%), specificity - 77.1%, 95% of DI (67.7%-84.3%), accuracy - 78.0%, 95% of CI (69.7%-84.5%), PPV – 66.1%, 95% of CI (54.0%-76.5%), NPV-of 87.1%, 95% of CI (78.3%-92.6%). Conclusion. The results of the analysis have shown that digital breast tomosynthesis has advantages in diagnostic efficiency in comparison with traditional mammography: higher accuracy and specificity because of an exception of superposition effect in identification of additional signs of diseases of the benign and malignant nature, including high mammography density. © 2019 Russian Electronic Journal of Radiology. All rights reserved.

Mikushin S.Yu. 1, 3 , Rozhkova N.I. 1, 3 , Grishkevich V.I.2 , Jakobs O.E. 1, 3 , Burdina I.I. 1 , Zapirova S.B. 1 , Mazo M.L. 1, 3 , Prokopenko S.P. 1
АНО Национальный конгресс лучевых диагностов
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  • 1 National Center of Oncology of Reproductive Organs., P.A. Herzen Federal Medical Research Center, branch of the of FSBI NMRRC of the Ministry of Health, Russian Federation
  • 2 OKDC PAO "Gazprom", Moscow, Russian Federation
  • 3 Peoples' Friendship University of Russia., Moscow, Russian Federation
Breast cancer; Diagnostics; Digital mammography; Tomosynthesis
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