Reaction of benzyne with 1,2,3,4-tetrahydroisoquinolines as an access to 1H-3-benzazepines

1,2,3,4-Tetrahydroisoquinolines bearing phenacyl group at the nitrogen atom in their reaction with benzyne in acetonitrile undergo ring expansion to give 1H-3-benzazepines. © 2018

Authors
Guranova N.I. 1 , Varlamov A.V. 1 , Novikov R.A. 2 , Aksenov A.V. 3 , Borisova T.N. 1 , Sorokina E.A. 1 , Voskressensky L.G. 1
Journal
Mendeleev Communications
Publisher
Royal Society of Chemistry
Issue number
1
Language
English
Pages
22-24
State
Published
Link
External link
DOI
10.1016/J.MENCOM.2018.01.005
Volume
28
Year
2018
Organizations
  • 1 Organic Chemistry Department, Peoples Friendship University of Russia (RUDN University), Moscow, 117198, Russian Federation
  • 2 N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, 119991, Russian Federation
  • 3 North-Caucasus Federal University, Stavropol, 355009, Russian Federation
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