Unsaturated carboxylic acids in the one-pot synthesis of novel derivatives of 3,4-dihydro-2H-thiopyran

[Figure not available: see fulltext.] The reactions of α,β-unsaturated ketones and Lawesson’s reagent with maleic, itaconic, or 5-norbornene-2,3-dicarboxylic acid led to the corresponding 3,4-dihydro-2H-thiopyran anhydrides. As a result of the reaction of methacrylic acid, Lawesson’s reagent, and chalcone, 4-methyl-1,8-diphenyl-2,6-dithiabicyclo[2.2.2]octan-3-one is formed. The selectivity of the acylation of amines using the synthesized anhydrides was studied. © 2021, Springer Science+Business Media, LLC, part of Springer Nature.

Authors
Merkulova E.А.1 , Kolobov A.V. 1 , Ovchinnikov K.L.1 , Khrustalev V.N. 2, 3 , Nenajdenko V.G. 4
Publisher
Латвийский институт органического синтеза Латвийской академии наук / Springer New York Consultants Bureau
Number of issue
3
Language
English
Pages
245-252
Status
Published
Volume
57
Year
2021
Organizations
  • 1 Yaroslavl State Technical University, 88 Moskovsky Ave., Yaroslavl, 150023, Russian Federation
  • 2 RUDN University, 6 Miklukho-Maklaya St., Moscow, 117198, Russian Federation
  • 3 N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave., Moscow, 119991, Russian Federation
  • 4 Lomonosov Moscow State University, 1, Build. 3 Leninskie Gory, Moscow, 119991, Russian Federation
Keywords
3,4-dihydro-2H-thiopyran; acylation; itaconic acid; Lawesson’s reagent; maleic acid
Date of creation
20.04.2021
Date of change
20.04.2021
Short link
https://repository.rudn.ru/en/records/article/record/72073/
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