Ultrastructural analysis of interactions of staphylococci with mono- and polynuclear phagocytes in nonphlogogenic and phlogogenic reaction

Antibacterial activity of neutrophils and peritoneal macrophages toward massive doses of Staphylococcus aureus is studied in vivo. Two types of antibacterial response are revealed: non-phlogogenic (physiological) and phlogogenic (inflammatory). Nonphlogogenic reaction is characterized by pronounced antibacterial effect of phagocytes on cocci. Transition to phlogogenic response is accompanied by impaired function of phagocytes involving their self-destruction and disintegration, which decreases their antibacterial activity and promotes inflammation. ©1998 Plenum Publishing Corporation.

Editors
-
Publisher
New York Consultants BureauSpringer / Автономная некоммерческая организация Издательство Российской академии медицинских наук
Number of issue
3
Language
English
Pages
304-308
Status
Published
Department
-
Number
-
Volume
125
Year
1998
Organizations
  • 1 Department of Pathological Anatomy, Russian University of Peoples Friendship, Moscow, Russian Federation
Keywords
Macrophage; Neutrophil; Phagolysosome; Staphylococcus
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/670/