Determination of the fluorescence intensity of coenzymes NADH and FAD in the skeletal muscle of the rat depending on the post-mortem interval

Aim of the study is to identify patterns of variations of the fluorescence intensity of NADH (reduced nicotinamide adenine dinucleotide) and FAD (oxidized flavin adenine dinucleotide) in the skeletal muscle depending on the time since death. For the evaluation of fluorescence intensity of the studied coenzymes, laser-induced spectroscopy in situ was used. We revealed the dynamic of the fluorescence intensity of NADH and FAD in the skeletal muscle of a rat at different times during the post-mortem period, and theoretically justified the observed phenomena. The results obtained allow us to consider the studied indicators as a potential criterion for determining the post-mortem interval. © 2020, Media Sphera Publishing Group. All rights reserved.

Authors
Babkina A.S. 1, 2 , Sundukov D.V. 1 , Golubev A.M. 1, 2 , Ryzhkov I.A.2 , Tsokolaeva Z.I.2 , Zarzhetsky Y.V.2
Number of issue
1
Language
Russian
Pages
31-35
Status
Published
Volume
63
Year
2020
Organizations
  • 1 Department of Forensic Medicine, Medical Institute of the Peoples’ Friendship University of Russia, Moscow, 117198, Russian Federation
  • 2 General resuscitation Research Center of the V.A. Negovsky Federal Scientific and Clinical Center of resuscitation and rehabilitation, Moscow, 107031, Russian Federation
Keywords
Coenzymes; FAD; Fluorescence; NADH; Post-mortem interval
Date of creation
02.11.2020
Date of change
02.11.2020
Short link
https://repository.rudn.ru/en/records/article/record/65447/
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