Research on the antibacterial and antimycotic effect of the phytopreparation farnesol on biofilm-forming microorganisms in veterinary medicine

Research has been conducted on farms in the Moscow region to identify the most common bacterial and fungal pathogens that can form biofilms. The following isolates were isolated from numerous members of the genus Candida: C. albicans, C. tropicalis, C. parapsilosis and C. glabrata. The etiological structure of bacterial infections in farm animals is represented by 29 species. The use of Farnesol 200 µm caused a decrease in the optical density of YLF biofilms from 54 to 69 % and a violation of mycelial growth.Farnesol 200 µm inhibited biofilm formation in strong bacterial producers by 61-75 %. Phytopreparation Farnesol can be used as an antibacterial and antimycotic drug both by itself and in combination with other antimicrobial agents. © 2020, Advanced Scientific Research. All rights reserved.

Publisher
Advanced Scientific Research
Language
English
Pages
1481-1492
Status
Published
Volume
12
Year
2020
Organizations
  • 1 Department of Veterinary Medicine, Agrarian Technological Institute, Peoples' Friendship University of Russia (RUDN University), Moscow, Russian Federation
  • 2 Biological Testing Laboratory, Branch of Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences (BIBCh RAS), Moscow region, Pushchino, Russian Federation
Keywords
Bacteria; Biofilms; Cows; Herbal medicine; Microscopic fungi; Optical density; Phytopreparation Farnesol; The genus Candida
Date of creation
02.11.2020
Date of change
30.09.2021
Short link
https://repository.rudn.ru/en/records/article/record/64551/
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Mikhalev V., Shabunin S., Vatnikov Y., Kulikov E., Byakhova V., Strachuk A., Kobylyanu G., Kochneva M., Petukhov N., Khairova N., Terekhin A., Dryemova T., Kondrashkina K.
International Journal of Pharmaceutical Research. Advanced Scientific Research. Vol. 12. 2020. P. 1856-1865