Influence of L-lysin-a-oxidase on the reproduction of herpes simplex virus type 1 in vitro

L-lysin-a-oxidase (LO), a fungal enzyme catalysing oxidative deamination of L-lysin, was used for the inhibition of the reproduction of herpes simplex virus type 1 (HSV-1). Antiviral activity of LO was tested in vitro. The expression of viral antigens and CPE of HSV-1 was inhibited by LO at a concentration 0,7 mg/ml.

Authors
Smirnova I.P. 1 , Diorditsa S.V. 1 , Alekceev S.B. 1 , Zaitsev I.Z. 1
Journal
Voprosy Meditsinskoj Khimii
Number of issue
4
Language
Russian
Status
Published
Link
External link
Volume
44
Year
1998
Organizations
  • 1 Department of Biochemistry, Russ. Peoples' Friendship University, Russian Federation
Keywords
Herpes virus; L-lysin-a-oxidase; Reproduction
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/621/
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