Cognition disorders in hypertensive patients of older age and senile

Aim. To assess cognitive status of the older age patients with arterial hypertension, in outpatient setting. Material and methods. Totally, 356 patients included, age 74,9±6,1 y., 80,4% females. For cognition assessment before and after the treatment, neuropsychological test was done, with MMSE - short scale of psychic status assessment, drawing test; literal and categoric associations test. Results. In the group <80 y. o. The prominence of MMSE disorders correlated with blood pressure values (BP): for systolic BP (r=-0,22, p=0,0003), for diastolic BP (r=-0,13, p=0,03), i. e. in higher BP patients there were lower points in cognition scale by Spearman correlation. In the group ≥80 y. both correlations were non-significant, for systolic BP (r=-0,05, p=0,64), and for diastolic BP (r=-0,13, p=0,25). Conclusion. In older age and senile patients with arterial hypertension there should be differential approach to BP management according to the age and cognition disorders, complex approach to treatment in these patients might prevent further worsening of cognitive decline.

Authors
Sharashkina N.V.1 , Ostapenko V.S.1 , Tkacheva O.N.1 , Runikhina N.K.1 , Kotovskaya Yu.V. 1, 2 , Mkhitarian E.A.1 , Lysenkov S.N.1, 3
Publisher
Vserossiiskoe Obshchestvo Kardiologov
Number of issue
3
Language
Russian
Pages
34-38
Status
Published
Volume
16
Year
2017
Organizations
  • 1 N. I. Pirogov Russian National Research Medical University (RNRMU), SD Russian Gerontological Scientific-Clinical Center, Moscow, Russian Federation
  • 2 Peoples' Friendship University of Russia, Moscow, Russian Federation
  • 3 Biological Faculty of the Lomonosov Moscow State University, Moscow, Russian Federation
Keywords
Arterial Hypertension; Cognition Disorders; Dementia; Senile.
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/6199/
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